Gerhard Möller

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The Gorham-Stout Syndrome (Gorham's massive osteolysis) is a rare condition in which spontaneous, progressive resorption of bone occurs. The aetiology is poorly understood. We report six cases of the condition and present evidence that osteolysis is due to an increased number of stimulated osteoclasts. This suggests that early potent antiresorptive therapy(More)
Berichtet wird über den seltenen Fall einer sog. massiven idiopathischen Osteolyse nach Gorham-Stout. Posttraumatisch kam es bei einer 77jährigen Patientin innerhalb von 2,5 Monaten zur Resorption des gesamten rechten Hüftkopfs und Schenkelhalses. Als Ursache für die Osteolyse konnte histologisch eine ausgeprägte Stimulation von Osteoklasten an der(More)
Radiographic studies to discriminate benign from malignant pulmonary masses have previously focused on the morphologic and, more recently, the computed tomographic (CT) attenuation characteristics of the lung mass. Experience with the use of an intravenously administered iodinated contrast medium in examining the enhancement properties of lung masses was(More)
One rare case of so-called massive idiopathic osteolysis Gorham-Stout is presented. In a 77-year-old female patient the whole right femoral head and neck of femur was resorbed within 2.5 month following trauma. As a histologic cause for the osteolysis, a marked stimulation of osteoclasts on the spongiosa, especially intracortically, was observed. The course(More)
Near-infrared spectroscopy (NIRS) can monitor changes in cerebral regional oxygen saturation (rSO2) and tissue hemoglobin content (HbT). The relation between cerebral NIRS readings and vital parameters has not been analyzed before at a fine temporal scale. This study analyzed this relation during cardiopulmonary bypass (CPB) surgery in 10 children (0–9(More)
Near infrared spectroscopy (NIRS) allows to study cerebral hemodynamics and oxygenation in neonates, which may be useful for early detection of cerebral hypoxemia. So far this method is not reliable enough to be used clinically. Reproducibility is one of the prerequisites for reliable quantitative monitoring. The aim of this study was to assess the(More)
Previous studies have compared the use of anticholinergic drugs and glucagon for upper gastrointestinal (UGI) radiography. Many radiologists prefer glucagon because these comparisons showed it to have a shorter duration of action with fewer side effects.l-Hyoscyamine is the levo-rotatory form of atropine with minor adverse side effects. This study compared(More)
The difficulty of the medical diagnostic task and the advantages of the computer as an aid in this task are discussed. The general strategy and structure of any computer-aided system is presented, and the relationship of diagnostic accuracy to key variables involved in the development, test and use of a computer-aided diagnostic system is examined. These(More)
GERHARD is a fully automatic indexing and classification system of the German WorldWide Web for integrated searching and browsing. A database-driven robot collects academically relevant documents, which are automatically classified with computer-linguistic and statistical methods using the Universal Decimal Classification. The generated metadata and the(More)