Gerhard K. Wolf

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Electrical impedance tomography (EIT) is an attractive method for clinically monitoring patients during mechanical ventilation, because it can provide a non-invasive continuous image of pulmonary impedance which indicates the distribution of ventilation. However, most clinical and physiological research in lung EIT is done using older and proprietary(More)
OBJECTIVE Regional differences in lung volume have been described in adults with acute respiratory distress syndrome, but it remains unclear to what extent they occur in children. To quantify regional alveolar collapse that occurred during mechanical ventilation during a standardized suctioning maneuver, we evaluated regional and global relative impedance(More)
OBJECTIVE Respiratory inductance plethysmography (RIP) and electrical impedance tomography (EIT) are two monitoring techniques that have been used to assess lung volume noninvasively. METHODS RIP uses two elastic bands around the chest and abdomen to assess global changes in lung volume. In animal models, RIP has been shown to detect changes in lung(More)
OBJECTIVES To investigate the electrical activity of the diaphragm during extubation readiness testing. DESIGN Prospective observational trial. SETTING A 29-bed medical-surgical pediatric intensive care unit. PATIENTS Mechanically ventilated children between 1 month and 18 yrs of age. INTERVENTIONS Twenty patients underwent a standardized extubation(More)
Breathing moves volumes of electrically insulating air into and out of the lungs, producing conductivity changes which can be seen by electrical impedance tomography (EIT). It has thus been apparent, since the early days of EIT research, that imaging of ventilation could become a key clinical application of EIT. In this paper, we review the current state(More)
OBJECTIVE To utilize real-time electrical impedance tomography to guide lung protective ventilation in an animal model of acute respiratory distress syndrome. DESIGN Prospective animal study. SETTING Animal research center. SUBJECTS Twelve Yorkshire swine (15 kg). INTERVENTIONS Lung injury was induced with saline lavage and augmented using large(More)
Myocarditis and malignant dysrhythmias are unusual presentations in pediatric patients. We report a series of 4 patients with myocarditis and arrhythmia who presented to community emergency departments and were transported to a pediatric tertiary-care center. Three of the patients required extracorporeal life support. We discuss considerations for(More)
Electrical impedance tomography (EIT) has undergone 30 years of development. Functional chest examinations with this technology are considered clinically relevant, especially for monitoring regional lung ventilation in mechanically ventilated patients and for regional pulmonary function testing in patients with chronic lung diseases. As EIT becomes an(More)
Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), also termed Hashimoto’s encephalopathy (HE), is a rare immune-mediated disorder and is also affecting children and adolescents. It is characterized by altered mental status, seizures, and cognitive dysfunction. Therapeutic options include steroid treatment and prognosis range(More)
OBJECTIVE To identify the effect of perflubron on gas exchange and lung mechanics during high frequency oscillatory ventilation in an animal model. DESIGN Prospective randomized animal trial. SUBJECTS Eighteen Yorkshire swine. INTERVENTIONS Three groups of six animals each were investigated: control (high frequency oscillatory ventilation alone), low(More)