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- GERGELY RÖST, JIANHONG WU
- 2007

The dynamics generated by the delay differential equation _ xðtÞZKmxðtÞC f ðxðtKtÞÞ with unimodal feedback is studied. The existence of the global attractor is shown and bounds of the attractor are given. We find attractive invariant intervals and give sufficient conditions that guarantee that all solutions enter the domain where f 0 is negative with… (More)

- Gergely Röst, Jianhong Wu
- Mathematical biosciences and engineering : MBE
- 2008

A new SEIR model with distributed infinite delay is derived when the infectivity depends on the age of infection. The basic reproduction number R0, which is a threshold quantity for the stability of equilibria, is calculated. If R0 < 1, then the disease-free equilibrium is globally asymptotically stable and this is the only equilibrium. On the contrary, if… (More)

- Gergely Röst
- 2004

In this paper we study the delay differential equation ˙ x(t) = (a(t)x(t) + f (t, x(t − 1))), where is a real parameter, the functions a(t), f (t,) are C 4-smooth and periodic in the variable t with period 1. Varying the parameter, eigenvalues of the monodromy operator (the derivative of the time-one map at the equilibrium 0) cross the unit circle and… (More)

- Yukihiko Nakata, Gergely Röst
- Journal of mathematical biology
- 2015

We formulate an epidemic model for the spread of an infectious disease along with population dispersal over an arbitrary number of distinct regions. Structuring the population by the time elapsed since the start of travel, we describe the infectious disease dynamics during transportation as well as in the regions. As a result, we obtain a system of delay… (More)

- Murray E Alexander, Christopher S Bowman, +5 authors Ping Yan
- Proceedings. Biological sciences
- 2007

Given the danger of an unprecedented spread of the highly pathogenic avian influenza strain H5N1 in humans, and great challenges to the development of an effective influenza vaccine, antiviral drugs will probably play a pivotal role in combating a novel pandemic strain. A critical limitation to the use of these drugs is the evolution of highly transmissible… (More)

- Seyed M. Moghadas, Christopher S. Bowman, Gergely Röst, Jianhong Wu
- PloS one
- 2008

BACKGROUND
The emergence of neuraminidase inhibitor resistance has raised concerns about the prudent use of antiviral drugs in response to the next influenza pandemic. While resistant strains may initially emerge with compromised viral fitness, mutations that largely compensate for this impaired fitness can arise. Understanding the extent to which these… (More)

- Murray E Alexander, Seyed M Moghadas, Gergely Röst, Jianhong Wu
- Bulletin of mathematical biology
- 2008

The use of antiviral drugs has been recognized as the primary public health strategy for mitigating the severity of a new influenza pandemic strain. However, the success of this strategy requires the prompt onset of therapy within 48 hours of the appearance of clinical symptoms. This requirement may be captured by a compartmental model that monitors the… (More)

- Seyed M Moghadas, Christopher S Bowman, Gergely Röst, David N Fisman, Jianhong Wu
- BMC medicine
- 2009

BACKGROUND
With the rise of the second pandemic wave of the novel influenza A (H1N1) virus in the current season in the Northern Hemisphere, pandemic plans are being carefully re-evaluated, particularly for the strategic use of antiviral drugs. The recent emergence of oseltamivir-resistant in treated H1N1 patients has raised concerns about the prudent use… (More)

- Istvan Z Kiss, Gergely Röst, Zsolt Vizi
- Physical review letters
- 2015

In this Letter, a generalization of pairwise models to non-Markovian epidemics on networks is presented. For the case of infectious periods of fixed length, the resulting pairwise model is a system of delay differential equations, which shows excellent agreement with results based on stochastic simulations. Furthermore, we analytically compute a new… (More)

- Eduardo Liz, Gergely Röst
- 2008

We give bounds for the global attractor of the delay differential equation ˙ x(t) = −µx(t) + f (x(t−τ)), where f is unimodal and has negative Schwarzian derivative. If f and µ satisfy certain condition, then, regardless of the delay, all solutions enter the domain where f is monotone decreasing and the powerful results for delayed monotone feedback can be… (More)