Gerda Bosman

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Prenatal diagnosis, management and outcome were studied retrospectively in 24 cases of unilateral and bilateral uretero-pelvic junction obstruction (UPJO). Moderate-to-marked pelvic dilatation was documented in 19 out of 24 cases. The low morbidity and mortality observed in this study are probably determined by the late (third trimester) detection of UPJO,(More)
BACKGROUND Resistance to carbapenem antibiotics is emerging worldwide among Enterobacteriaceae. To prevent hospital transmission due to unnoticed carriage of carbapenemase producing micro-organisms in newly admitted patients, or follow-up of patients in an outbreak setting, a molecular screening method was developed for detection of the most prevalent(More)
With interest we read the case report by Wijsman, et al. In addition to their patients, we describe a 21-year-old woman with a systemic inflammatory response syndrome (SIRS) and pancytopenia after a primary Epstein-Barr virus (EBV) infection. Three weeks earlier she had been admitted elsewhere with fever, anorexia, cervical lymphadenopathy, jaundice, rash(More)
Background/Methods. Marfan syndrome (MFS) is a heritable connective tissue disorder usually caused by a mutation in the fibrillin 1 (FBN1) gene. Typical characteristics of MFS that have been described include dolichostenomelia, ectopia lentis and aortic root dilatation. However, there is great clinical variability in the expression of the syndrome's(More)
The immunoreactivity of erythrocyte band 3 (B3-IR)-related protein was estimated on cortex biopsies from the brains of 33 patients varying in age from 14-week-old fetus until 67 years of life. B3-IR was not a feature of embryonic brains. A positive reaction was restricted to neurons. It appeared at early postnatal life, increased sharply until 9 years, and(More)
Erythrocyte structure and function depend upon interactions between proteins in and associated with the membrane, centered around band 3. This protein harbours physiological removal signals and, as a main component of the links between the cytoskeleton and the lipid bilayer, plays a central role in deformability. Also, as a binding partner of hemoglo-bin(More)
BACKGROUND The objective of our study was the development of a semi-quantitative real-time PCR to detect uropathogens. Two multiplex PCR reactions were designed to detect Escherichia coli, Klebsiella spp., Enterobacter spp., Citrobacter spp., Proteus mirabilis, Enterococcus faecalis, and Pseudomonas aeruginosa. 16S based PCR was performed in parallel to(More)