OBJECTIVE
The 1987 American College of Rheumatology (ACR; formerly the American Rheumatism Association) classification criteria for rheumatoid arthritis (RA) have been criticised for their lack of… (More)
In this article, the 2010 European League against Rheumatism (EULAR) recommendations for the management of rheumatoid arthritis (RA) with synthetic and biological disease-modifying antirheumatic… (More)
Treatment of rheumatoid arthritis (RA) may differ among rheumatologists and currently, clear and consensual international recommendations on RA treatment are not available. In this paper… (More)
BACKGROUND
Aiming at therapeutic targets has reduced the risk of organ failure in many diseases such as diabetes or hypertension. Such targets have not been defined for rheumatoid arthritis (RA).
… (More)
OBJECTIVE
To determine the efficacy and safety of treatment with rituximab plus methotrexate (MTX) in patients with active rheumatoid arthritis (RA) who had an inadequate response to anti-tumor… (More)
BACKGROUND
Certolizumab pegol is a PEGylated tumour necrosis factor inhibitor.
OBJECTIVE
To evaluate the efficacy and safety of certolizumab pegol versus placebo, plus methotrexate (MTX), in… (More)
These include: References http://ard.bmj.com/cgi/content/full/65/suppl_3/iii2#BIBL This article cites 240 articles, 58 of which can be accessed free at: Rapid responses… (More)
BACKGROUND
Cyclo-oxygenase 2 (COX2)-selective inhibitors should reduce ulcer complications compared with non-selective non-steroidal anti-inflammatory drugs, but evidence is limited, and the… (More)
1. Introduction Within the past decade, musculoskeletal ultra-sound (US) has become an established imaging technique for the diagnosis and follow up of patients with rheumatic diseases. 1–5 This has… (More)
BACKGROUND
The potential for cyclo-oxygenase 2 (COX2)-selective inhibitors to increase the risk for myocardial infarction is controversial. The Therapeutic Arthritis Research and Gastrointestinal… (More)