Gerd Bayer

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A 37-year-old woman was admitted after 3 days of fever, cough and diffuse pain. She had a 6-month history of relapsing polychondritis treated with steroids and, initially, cyclophosphamide. Cyclophosphamide was stopped after the third infusion due to anaphylactic shock and replaced by mycophenolate mofetil. On physical examination, she had dyspnea with(More)
AIMS The vascular effects of drug- eluting balloon (DEB) deployment in the absence of coronary stents have not been characterised. This study evaluated potential vascular effects of paclitaxel-coated angioplasty balloons using different excipients in the absence of additional stents. METHODS AND RESULTS A total 45 porcine arteries were treated with(More)
The advent of drug-eluting balloon (DEB) therapy has represented an important development in interventional cardiology. Nevertheless, preclinical data with this technology remain scant, and comparative studies have not previously been published. Bare metal stents were implanted in the coronary arteries of 15 pigs followed by balloon angioplasty. Animals(More)
Biodegradable stent coatings were recently introduced as a potential solution to overcome sustained inflammatory responses observed with permanent polymer-based drug-eluting stents. In a preliminary study, selected biodegradable or permanent polymer-based sirolimus-eluting stent (SES) formulations were screened for effectiveness in comparison to bare metal(More)
AIMS The purpose of the present study was to examine the comparative vascular healing response to stents coated with permanent or biodegradable polymer and uncoated stents in a porcine model of coronary artery stenting. METHODS AND RESULTS Juvenile pigs were randomly allocated to implantation of stents coated with permanent polymer (PP,(More)
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