Gerben Schooneveldt

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BACKGROUND AND PURPOSE The effectiveness of locoregional hyperthermia combined with intravesical instillation of mitomycin C to reduce the risk of recurrence and progression of intermediate- and high-risk nonmuscle-invasive bladder cancer is currently investigated in clinical trials. Clinically effective locoregional hyperthermia delivery necessitates(More)
Introduction The reliability of hyperthermia treatment planning (HTP) is strongly dependent on the accuracy of the electric properties of each tissue. The values currently used are mostly based on ex vivo measurements. In this study, in vivo conductivity of human muscle, bladder content and cervical tumours, acquired with magnetic resonance-based electric(More)
PURPOSE Hyperthermia combined with Mitomycin C is used for the treatment of non-muscle invasive bladder cancer (NMIBC), using a phased array system of microwave antennas for bladder heating. Often some air is present in the bladder, which effectively blocks the microwave radiation, potentially preventing proper treatment of that part of the bladder. Air can(More)
Recently, new theories have been developed to solve the hierarchy problem (i.e. why gravity is so much weaker than electromagnetism). These theories use a higher dimensional spacetime. We review the theoretical framework of these scenarios, their implications in shortrange gravity and collider experiments, and finally their cosmological and astrophysical(More)
PURPOSE The aim of this study is to develop and validate a generic method for automatic bladder segmentation on cone beam computed tomography (CBCT), independent of gender and treatment position (prone or supine), using only pretreatment imaging data. METHODS Data of 20 patients, treated for tumors in the pelvic region with the entire bladder visible on(More)
PURPOSE Hyperthermia is an established (neo)adjuvant treatment modality for a number of pelvic malignancies. Optimal treatment of these tumors requires robust treatment planning, but up until now, the urinary bladder was not modeled accurately, making current simulations less reliable. The authors improved the dielectric and thermophysical model of the(More)
PURPOSE Adaptive radiotherapy (ART) with a plan-of-the-day (PotD) approach is suitable for cervical cancer patients, due to the highly mobile cervix-uterus. PotD selection is not obvious given the poor soft-tissue contrast of CBCT and bladder volume can be used as indirect measure of cervix-uterus position. The aim of this study is to automatically segment(More)
The urinary bladder is a fluid-filled organ. This makes, on the one hand, the internal surface of the bladder wall relatively easy to heat and ensures in most cases a relatively homogeneous temperature distribution; on the other hand the variable volume, organ motion, and moving fluid cause artefacts for most non-invasive thermometry methods, and require(More)
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