Gerard Macias

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We describe a new method for the immobilisation of DNA into defined patterns with sub-micron resolution, using the fluorous effect. The method is fully reversible via a simple solvent wash, allowing the patterning, regeneration and re-patterning of surfaces with no degradation in binding efficiency following multiple removal/attachment cycles of different(More)
Materials. HPLC-purified DNA oligomers with several different modifications (Table 1) were purchased from Integrated DNA Technologies (IDT). Ultrapure water (18.2 MΩ.cm) was used for all solutions and protocols. All chemicals were obtained from Sigma unless otherwise stated. The oligomers were diluted to final concentrations in TE buffer and concentrations(More)
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