Gerald Steiner

Ortrud Uckermann6
Gabriele Schackert4
6Ortrud Uckermann
4Gabriele Schackert
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  • Roberta Galli, Ortrud Uckermann, Elisabeth F. Andresen, Kathrin D. Geiger, Edmund Koch, Gabriele Schackert +3 others
  • 2014
Multiphoton imaging has evolved as an indispensable tool in cell biology and holds prospects for clinical applications. When addressing endogenous signals such as coherent anti-Stokes Raman scattering (CARS) or second harmonic generation, it requires intense laser irradiation that may cause photodamage. We report that increasing endogenous fluorescence(More)
  • Ortrud Uckermann, Roberta Galli, Sandra Tamosaityte, Elke Leipnitz, Kathrin D. Geiger, Gabriele Schackert +3 others
  • 2014
BACKGROUND Coherent anti-Stokes Raman scattering (CARS) microscopy provides fine resolution imaging and displays morphochemical properties of unstained tissue. Here, we evaluated this technique to delineate and identify brain tumors. METHODS Different human tumors (glioblastoma, brain metastases of melanoma and breast cancer) were induced in an orthotopic(More)
  • Allison L. Stelling, Deirdre Toher, Ortrud Uckermann, Jelena Tavkin, Elke Leipnitz, Julia Schweizer +4 others
  • 2013
In this work, the infrared (IR) spectra of living neural cells in suspension, native brain tissue, and native brain tumor tissue were investigated. Methods were developed to overcome the strong IR signal of liquid water so that the signal from the cellular biochemicals could be seen. Measurements could be performed during surgeries, within minutes after(More)
  • Sandra Tamosaityte, Roberta Galli, Ortrud Uckermann, Kerim H. Sitoci-Ficici, Robert Later, Rudolf Beiermeister +9 others
  • 2015
Spinal cord injury (SCI) induces complex biochemical changes, which result in inhibition of nervous tissue regeneration abilities. In this study, Fourier-transform infrared (FT-IR) spectroscopy was applied to assess the outcomes of implants made of a novel type of non-functionalized soft calcium alginate hydrogel in a rat model of spinal cord hemisection (n(More)
  • Ortrud Uckermann, Roberta Galli, Rudolf Beiermeister, Kerim-Hakan Sitoci-Ficici, Robert Later, Elke Leipnitz +6 others
  • 2015
Activation of CNS resident microglia and invasion of external macrophages plays a central role in spinal cord injuries and diseases. Multiphoton microscopy based on intrinsic tissue properties offers the possibility of label-free imaging and has the potential to be applied in vivo. In this work, we analyzed cellular structures displaying endogenous(More)