Gerald Steiner

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In this work, the infrared (IR) spectra of living neural cells in suspension, native brain tissue, and native brain tumor tissue were investigated. Methods were developed to overcome the strong IR signal of liquid water so that the signal from the cellular biochemicals could be seen. Measurements could be performed during surgeries, within minutes after(More)
Multiphoton imaging has evolved as an indispensable tool in cell biology and holds prospects for clinical applications. When addressing endogenous signals such as coherent anti-Stokes Raman scattering (CARS) or second harmonic generation, it requires intense laser irradiation that may cause photodamage. We report that increasing endogenous fluorescence(More)
BACKGROUND Coherent anti-Stokes Raman scattering (CARS) microscopy provides fine resolution imaging and displays morphochemical properties of unstained tissue. Here, we evaluated this technique to delineate and identify brain tumors. METHODS Different human tumors (glioblastoma, brain metastases of melanoma and breast cancer) were induced in an orthotopic(More)
Requestor: Enclosed per your request is a copy of the new second edition of " General The new guideline provides increased detail about construction and-operation of a system, general tables on sizing a system design, and guidance on cold weather applications. Information contained in the guideline represents the views of the authors, and revisions from the(More)