Gerald Merwin

Learn More
We compared the gross behavior of and microscopic response to implant materials currently in clinical use for facial bone augmentation at different sites in dogs. Materials evaluated include porous polytetrafluoroethylene carbon (Proplast), large-pore high-density polyethylene (Medpor), solid medical-grade silicone rubber (Silastic), polyamide mesh(More)
Fifty-six hospitalized geriatric patients between the ages of 65 and 80 were given piracetam (Nootropil) 2400 mg/day or placebo on a double blind basis over a two month period. Every patient submitted to a battery of psychological tests before and after the two month trial. These tests included the Similarities, Vocabulary, Digit Symbol, and Block Design(More)
Postlaryngectomy speech rehabilitation more frequently includes surgical-prosthetic methods since the introduction of a low morbidity tracheoesophageal puncture technique and a one-way airflow valve. This study compares speech using an artificial larynx and, in one case, esophageal speech with speech using a tracheoesophageal puncture and valve in the same(More)
Four biomaterials, UF45S5 Bioglass, Silastic, Plasti-Pore, and Proplast, were used to replace the incus in a mouse ear model. Bioglass, a bioactive glass ceramic, compared favorably with the other test materials in maintaining surgical positioning between malleus and stapes and remaining stable to a blast of nitrogen gas and to pick manipulation. In a(More)
Local cerebral glucose utilization was measured by the [14C]-deoxyglucose method in five near-term fetal sheep in whom bilateral ablation of the cochleae had been accomplished aseptically 5 to 8 days earlier. The tympanic membrane and ossicles were removed and all turns of each cochlea were unroofed with destruction carried to the modiolus. Mean local(More)
  • G E Merwin
  • The Annals of otology, rhinology, and laryngology
  • 1986
The current status of materials for use in middle ear reconstruction is discussed with particular emphasis given to alloplastic implants including bioinert and bioactive materials. Bioglass is a bioactive transparent glass which forms a bond with living tissues. Its development and characteristics are discussed, and the early results of a clinical trial(More)
This study investigated the effects of hyperbaric oxygen (HBO) and irradiation (RT) on experimental skin flaps in rats under varying conditions. Animals were assigned at random to 1 of 15 groups that represented all possible ordering effects of HBO, RT, and flap, as well as controls that included flap-only, RT-only, and HBO-only groups. Cranially based skin(More)
In the quest for a material other than autograft and homograft bone for use in facial augmentation and replacement, materials scientists have developed numerous inert materials, some of which have a porous structure allowing scar tissue ingrowth to aid in stabilization of the implant. This study investigates a bioactive, nonporous, transparent glass(More)