Gerald Hüther

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This review summarizes some important principles of human brain development. Special emphasis is placed on the role of psychosocial stress during childhood on the developing brain. Depending on the degree of cognitive, behavioral and socio-emotional maturation, previous experiences and actual context, psychosocial stressors may be perceived by children as(More)
The pattern of the multiple forms of the acetylocholinesterase (AChE, E.C. 3.1.1.7) of the rat brain is investigated using polyacrylamide gradient micro-gel electrophoresis with regard to a possible functional importance of this individual forms. The patterns of the AChE-forms of selected regions of the CNS are compared and certain differences could be(More)
The most important finding made in the field of neurobiological research during the last decade is the discovery of the enormous experience-dependent plasticity of the human brain. The elaboration and stabilization of synaptic connectivity, and therefore, the complexity of neuronal networks in the higher brain centres depend to a far greater extent than(More)
Recent progress in brain research has shown that the human brain, i.e., the neuronal and synaptic connectivity especially in higher cortical association centres, is much more plastic and use-dependent than previously thought. This contribution summarizes the present knowledge about this phenomenon of experience-dependent plasticity. Irritation, anxiety and(More)
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