Geotz Krauter

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Treatment of murine epidermis with the tumor promotor 12-O-tetradecanoylphorbol-13-acetate (TPA) shows characteristic and significant changes in protein expression analyzed by 2D PAGE, compared to(More)
We have proposed that c e l l u l a r senescence is cont ro l led by normal genes that are act ivated or whose funct ions become manifest at the end of the l i f e span of a ce l l . Defects in these(More)
In vitro incubation of mouse epidermis homogenate with arachidonJc acid shows the production of small amounts of 8-HETE and 12-HETE by 8and 12-1ipoxygenase, r~tively. To investigate the tissue levels(More)
For protein kinase C (PKC), a family of isoenzymes with serine/threonine-kinase activity identified as the major cellular receptor for certain skin irritants and tumor promoters, a new pharmacophore(More)
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