Georgios Kontopoulos

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OBJECTIVE To assess the bioequivalence of 2 oral isotretinoin (20 mg) soft gel capsule formulations. The reference preparation was Roaccutan/Roche while the test preparation was A-Cnotren/Pharmaten, Athens, Greece. SUBJECTS, MATERIAL AND METHODS The study was an open, randomized, 2-period, 2-sequence, 2-treatment crossover, involving 38 healthy male(More)
An open, two-period, randomized, crossover trial of two lisinopril (1-[N2-[(S)-1-carboxyl-3-phenylpropyl]-L-lysil]-L-proline, CAS 76547-98-3) formulations (Adicanil as test and another commercially available preparation as reference) was performed in 24 healthy volunteers. A single 20 mg oral dose of lisinopril was administrated and pharmacokinetic(More)
OBJECTIVE To assess the bioequivalence of 2 oral cefuroxime axetil (250 mg) tablets formulation. The reference preparation was Zinadol/Glaxo Wellcome, England, while the test preparation was cefuroxime axetil/Pharmathen, Athens, Greece. SUBJECTS, MATERIAL AND METHODS The study was an open, randomized, 2-period, 2-sequence, 2-treatment crossover, involving(More)
There is currently unprecedented interest in quantifying variation in thermal physiology 9 among organisms in order to understand and predict the biological impacts of climate change. A key parameter in this quantification of thermal physiology is the performance or value of a trait, across individuals or species, at a common temperature (temperature(More)
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