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Genome-wide expression profiling is a powerful tool for implicating novel gene ensembles in cellular mechanisms of health and disease. The most popular platform for genome-wide expression profiling is the Affymetrix GeneChip. However, its selection of probes relied on earlier genome and transcriptome annotation which is significantly different from current(More)
In the present work, a practical method for determination of the basic physicochemical parameters of beer-real extract, alcohol and biomass concentration based on the amount of produced CO 2 during the fermentation is investigated. The method was applied for determination of biomass concentration in immobilized preparations after its approbation with(More)
A detailed investigation of bioengineering constants for the accumulation of major yeast metabolites in beer produced by free and immobilized cells was carried out. The kinetic constants were used to determine the effect of immobilization on yeast metabolism. The esters synthesis dynamics was similar for the free and the immobilized cell which was confirmed(More)
Two mathematical models were developed for studying the effect of main fermentation temperature (T MF), immobilized cell mass (M IC) and original wort extract (OE) on beer fermentation with alginate-chitosan microcapsules with a liquid core. During the experiments, the investigated parameters were varied in order to find the optimal conditions for beer(More)
The aim of this work is to describe the kinetics of yogurt starter culture production by S.thermophilus 13ɚ and Lb. bulgaricus 2-11 and to quantitatively analyse the effect of different dissolved oxygen concentration in the milk on the process trend. Five different mathematical models for description of process kinetics are tested and the best one is(More)
A mathematical model was developed for studying the carbonyl compounds synthesis and reduction in beer fermentation with alginate-chitosan microcapsules with liquid core. The model was based on the results for the influence of the fermentation temperature, original wort gravity and immobilized cells mass on the carbonyl compounds synthesis and reduction.(More)
During past decades, several sequence comparison techniques, such as Smith-Waterman, FASTA, BLAST, and Suffix-arrays, etc. have been developed and widely used for genomic database searching. These algorithms are based on applying the string edit distance for genome sequence retrieval, and rely on sequence-string similarity between the query sequence and the(More)
An integrated approach for the management of continuous beer fermentation with immobilized cells was developed. Experimental results for continuous fermentation were used for the development of dependencies for the calculation of real extract and ethanol at different degrees of fermentation and dilution rates. For this purpose, mathematical relationships(More)