Georges Janssens

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1. Li, H., Ruan, J. & Durbin, R. Genome Res. 18, 1851–1858 (2008) 2. Hormozdiari, F. et al. Genome Res. (in the press). 3. Korbel, J.O. et al. Genome Biol. 10, R23 (2009). 4. Lee, S., Cheran, E. & Brudno, M. Bioinformatics 24, i59–i67 (2008). 5. Mills, R.E. et al. Genome Res. 16, 1182–1190 (2006). 6. Bentley, D.R. et al. Nature 456, 53–59 (2008). 7. Kidd,(More)
Multiple studies characterizing the human ageing phenotype have been conducted for decades. However, there is no centralized resource in which data on multiple age-related changes are collated. Currently, researchers must consult several sources, including primary publications, in order to obtain age-related data at various levels. To address this and(More)
Recent technological advances that allow faster and cheaper DNA sequencing are now driving biological and medical research. In this review, we provide an overview of state-of-the-art next-generation sequencing (NGS) platforms and their applications, including in genome sequencing and resequencing, transcriptional profiling (RNA-Seq) and high-throughput(More)
Large-scale RNAi-based screens are a major technology, but require adequate prioritization and validation of candidate genes from the primary screen. In this work, we performed a large-scale pooled shRNA screen in mouse embryonic stem cells (ESCs) to discover genes associated with oxidative stress resistance and found several candidates. We then developed a(More)
Corneal ulcers are probably the most common problem of the canine eye seen in general veterinary practice. Most of these ulcers result from a variety of traumatic and irritating conditions and usually respond well to medical therapy alone, provided they are not too deep. However, indolent ulcers are different: they are chronic superficial ulcers that result(More)
The authors tried to assess whether differentiating aspects of the treatment ideology of two therapeutic communities (psychoanalytic-psychotherapeutic and orthopedagogical were realised in the actual psychosocial milieux of the communities. Hypotheses were constructed about the differences in treatment ideology between the two communities, on the results on(More)
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