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Five neonates who were born at term and who had well-defined cystic lesions in the subependymal germinal matrix demonstrated by real-time cranial ultrasonography are reported. None had evidence of subependymal or intraventricular hemorrhage. Two of the neonates had congenital viral infections, one each with rubella virus and cytomegalovirus. Two of the(More)
Prediction of protein structures continues to be a difficult problem, particularly when there are no solved structures for homologous proteins to use as templates. Local structure prediction (secondary structure and burial) is fairly reliable, but does not provide enough information to produce complete three-dimensional structures. Residue-residue contact(More)
Controversy exists concerning the degree of importance of periventricular intraparenchymal echodensities (IPE) observed on neonatal ultrasound scans in the determination of subsequent neurologic disability in premature infants. In this report, IPE was studied in 75 infants weighing less than 2,000 g at birth to determine the basic characteristics of the(More)
Seven patients with left-sided congenital diaphragmatic hernias at ages of 2--20 months are reported and five are described in detail. Radiographic findings were classic in one patient, but simulated inflammatory chest disease in two patients, gastric volvulus in three patients, and a pneumothorax in one patient. These misleading appearances if not(More)
In a 3-yr period, eight infants among 43 survivors of acute NEC developed intestinal stricture. Four infants developed multiple stricture after proximal diversion procedures, and four had single strictures after medical therapy. Nineteen cases of intestinal stricture after NEC were collected from the literature. Radiographic examinations at the time of the(More)
The systemic manifestations of "asphyxia" were evaluated prospectively in 35 consecutively intubated term newborn infants. The following systemic organ injuries were identified most often: (1) renal, ie, oliguria less than 1 mL/kg per hour for at lest 24 hours (40%), an elevated urinary beta-2-microglobulin concentration (57%), azotemia (11%), and an(More)
Twenty-two patients with Henoch-Schonlein syndrome are reviewed, and four unusual cases are reported in detail. Henoch-Schonlein syndrome represents a diagnostic problem when abdominal manifestations precede cutaneous lesions and suggest a surgical abdomen. Unusual radiographic features such as changes in the small bowel identical to Crohn disease or(More)