George S. Davidson

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A clustering and ordination algorithm suitable for mining extremely large databases, including those produced by microarray expression studies, is described and analyzed for stability. Data from a yeast cell cycle experiment with 6000 genes and 18 experimental measurements per gene are used to test this algorithm under practical conditions. The process of(More)
We present the application of our knowledge visualization tool, VxInsight ® , to enable domain analysis for science and technology management within the enterprise. Data mining from sources of bibliographic information is used to define subsets of information relevant to a technology domain. Relationships between the individual objects (e.g. articles) are(More)
Digital libraries stand to benefit from technology insertions from the fields of information visualization, human-computer interaction, and cognitive psychology, among others. However, the current state of interaction between these fields is not well understood. We use our knowledge visualization tool, VxInsight ® , to provide several domain visualizations(More)
The explosive growth in the availability of information is overwhelming traditional information management systems. Although individual pieces of information have become easy to find, the larger context in which they exist has become harder to track. These contextual questions are ideally suited to visualization since the human visual system is remarkably(More)
In researching the communication mechanisms between cells of the immune system, visualization of proteins in three dimensions can be used to determine which proteins are capable of interacting with one another at a given time by showing their spatial colocality. Volume data sets are created using digital confocal immunofluorescence micros-copy. A variety of(More)
  • Sara D. Lawhon, Sangeeta Khare, Carlos A. Rossetti, Robin E. Everts, Cristi L. Galindo, Sarah A. Luciano +9 others
  • 2011
Salmonella enterica Serovar Typhimurium (S. Typhimurium) causes enterocolitis with diarrhea and polymorphonuclear cell (PMN) influx into the intestinal mucosa in humans and calves. The Salmonella Type III Secretion System (T3SS) encoded at Pathogenicity Island I translocates Salmonella effector proteins SipA, SopA, SopB, SopD, and SopE2 into epithelial(More)
The U.S. Department of Energy recently announced the first five grants for the Genomes to Life (GTL) Program. The goal of this program is to "achieve the most far-reaching of all biological goals: a fundamental, comprehensive, and systematic understanding of life." While more information about the program can be found at the GTL website(More)
As yeast cultures enter stationary phase in rich, glucose-based medium, differentiation of two major subpopulations of cells, termed quiescent and nonquiescent, is observed. Differences in mRNA abundance between exponentially growing and stationary-phase cultures and quiescent and nonquiescent cells are known, but little was known about protein abundance in(More)
OBJECTIVE An experiment was conducted to compare the effectiveness of individual versus group electronic brainstorming to address difficult, real-world challenges. BACKGROUND Although industrial reliance on electronic communications has become ubiquitous, empirical and theoretical understanding of the bounds of its effectiveness have been limited.(More)