George Qiu

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Hyaluronic acid (HA) synthesized by normal human epidermal keratinocytes cultured in a serum-free medium was monitored by a highly sensitive HPLC method, which was established by us for the simultaneous determination of HA, chondroitin sulfate (ChS) and dermatan sulfate (DS) as their unsaturated disaccharides. The major glycosaminoglycan (GAG) in the medium(More)
The structural diversity of dermatan sulphate (DS), the major glycosaminoglycan component of mammalian skin, was investigated by examining different layers of porcine dermal tissue using 1H-NMR and disaccharide compositional analysis by HPLC. Structural reporter signals were assigned using one-dimensional (1D) 1H-NMR differential transient NOE and 1D(More)
Dermatan sulfate-proteoglycans (DS-PGs) were extracted from rabbit, rat and bovine defatted livers by magnesium chloride extraction and DEAE-cellulose chromatography, and then submitted successively to Asahipak GS-520 gel filtration chromatography, Asahipak ES-502N anion exchange chromatography, and cellulose acetate membrane electrophoresis. The(More)
An ion-exchange high-performance liquid chromatography procedure was developed for analysis of mixtures of N-acetyldermosine, N-acetylchondrosine and N-acetylhyalobiuronic acid produced quantitatively by heating dermatan sulfate, chondroitin sulfate and hyaluronan in dimethyl sulfoxide (DMSO) containing 0.1% (v/v) H20 at 80 degrees C for 48 h. These(More)
Dermatan sulfate excreted in normal human urine was isolated and characterized by TLC and cellulose acetate strip electrophoresis after cetylpyridinium chloride precipitation and pronase digestion. In these separation methods, dermatan sulfate and chondroitin sulfate were extracted and then monitored by sensitive HPLC methods with post column fluorometric(More)
Glycosaminoglycan (GAG) synthesis by cultured normal human dermal fibroblasts was examined. Hyaluronic acid (HA) synthesis reached a maximum on day 3 (0.3 microgram/ml medium) and then decreased to a low level (0.15 microgram/ml medium). The amounts of dermatan sulfate (DS) and chondroitin sulfate (ChS) synthesized by the cells increased with increasing(More)
  • Yubo Chu, Chia-Wei Barbastathis, +9 authors Cheng Qiu
  • 2017
The unique superiority of transformation optics devices designed from coordinate transformation is their capability of recovering both ray trajectory and optical path length in light manipulation. However, very few experiments have been done so far to verify this dual-recovery property from viewpoints of both ray trajectory and optical path length(More)
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