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Northwestern blot analysis in the presence of competitor RNA was used to examine the interaction between the mouse hepatitis virus (MHV) nucleocapsid protein (N) and virus-specific RNAs. Our accompanying article demonstrates that anti-N monoclonal antibodies immunoprecipitated all seven MHV-specific RNAs as well as the small leader-containing RNAs from(More)
OBJECTIVE To interrupt transmission of Serratia marcescens colonization in a neonatal intensive care unit and determine the source of ongoing transmission. DESIGN Multidisciplinary outbreak investigation and simulation of droplet generation by a high-frequency oscillator using fluorescent dye. SETTING Level III neonatal intensive care unit. PATIENTS(More)
We have developed a new haplotyping program based on the combination of an iterative multiallelic EM algorithm (IEM), bootstrap resampling and a pseudo Gibbs sampler. The use of the IEM-bootstrap procedure considerably reduces the space of possible haplotype configurations to be explored, greatly reducing computation time, while the adaptation of the Gibbs(More)
BACKGROUND The United States Territory of Guam reported a large mumps outbreak of 505 cases during 2009-2010. We assessed the economic impact of the outbreak from the perspectives of the local public health sector and affected families. METHODS Using standard cost analysis methods, we retrospectively identified all public health personnel involved in the(More)
BACKGROUND Despite high 2-dose measles-mumps-rubella (MMR) vaccine coverage, a large mumps outbreak occurred on the US Territory of Guam during 2009 to 2010, primarily in school-aged children. METHODS We implemented active surveillance in April 2010 during the outbreak peak and characterized the outbreak epidemiology. We administered third doses of MMR(More)
Causal and responsibility attributions for spouse behavior are examined in couples seeking therapy and in nondistressed community couples. Eighty spouses rated the causes of positive and negative partner behaviors, made attributions of responsibility for the behaviors, indicated their affective impact, and, finally, specified what they would do in response(More)
BACKGROUND South Africa introduced 7-valent pneumococcal conjugate vaccine (PCV7) in April 2009 using a 2 + 1 schedule (6 and 14 weeks and 9 months). We estimated the effectiveness of ≥2 PCV7 doses against invasive pneumococcal disease (IPD) in human immunodeficiency virus (HIV)-infected and -uninfected children. METHODS IPD (pneumococcus identified from(More)
A study was performed to identify epidemiological factors such as age, race, sex, and time of culture that might influence the ability of the normal pharyngeal flora to interfere with growth of group A streptococci. From March 1974 through February 1975, throat swabs were obtained from 952 individuals. Cultures were assayed by an agar overlay procedure for(More)