George N. Vaughan

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1 Thirty clonidine- and tolazoline-like compounds with differing phenyl ring substituents were tested for agonistic actions at histamine H1-receptors (guinea-pig ileum), histamine H2-receptors (guinea-pig driven right ventricular strips), post-junctional alpha-adrenoceptors (rat desheathed was deferens) and pre-junctional alpha-adrenoceptors (inhibition of(More)
. depression of sertim thyroid hormones 2 weeks after Lnjury. Thyroidectomized rats had a marked rise in brain in vitro T4 f deiodination to T3 and in serum TSH concentration compared to controls. These normal responses to depressed thyroid hormones were S not seen in burned rats. The depression of serum thyronines and thyrotrophin suggests that the burned(More)
A highly efficient ion-pair extraction technique for the isolation of tryptamine, 5-hydroxytryptamine, and their mono- and N,N-dimethylated derivatives from aqueous media is described. The technique has been used to isolate nanogram quantities of both N, N-dimethyltryptamine and 5-hydroxy-N, N-dimethyltryptamine from large volumes of urine. A rapid and(More)
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