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  • George M Carman, Susan A Henry
  • Biology, Medicine
  • Journal of Biological Chemistry
  • 2007 (First Publication: 28 December 2007)
  • In eukaryotic cells, PA2 is a central precursor for the synthesis of major glycerophospholipids, DAG and TAG, as well as a major signaling lipid. In mammalian cells, PA is implicated as an activatorContinue Reading
  • Gil-Soo Han, Symeon Siniossoglou, George M Carman
  • Biology, Medicine
  • Journal of Biological Chemistry
  • 2007 (First Publication: 21 December 2007)
  • The Saccharomyces cerevisiae PAH1-encoded Mg2+-dependent phosphatidate phosphatase (PAP1, 3-sn-phosphatidate phosphohydrolase, EC 3.1.3.4) catalyzes the dephosphorylation of phosphatidate to yieldContinue Reading
  • Gil-Soo Han, Laura O'Hara, George M Carman, Symeon Siniossoglou
  • Medicine, Biology
  • Journal of Biological Chemistry
  • 2008 (First Publication: 18 July 2008)
  • Changes in nuclear size and shape during the cell cycle or during development require coordinated nuclear membrane remodeling, but the underlying molecular events are largely unknown. We have shownContinue Reading
  • Hyeon-Son Choi, Wen-Min Su, +5 authors George M Carman
  • Medicine, Biology
  • The Journal of Biological Chemistry
  • 2010 (First Publication: 16 November 2010)
  • The Saccharomyces cerevisiae PAH1-encoded phosphatidate phosphatase (PAP) catalyzes the penultimate step in the synthesis of triacylglycerol and plays a role in the transcriptional regulation ofContinue Reading