George Ku

Annamaria Vezzani2
Silvia Balosso2
Teresa Ravizza2
Liliana Bernardino2
Stuart Allan1
2Annamaria Vezzani
2Silvia Balosso
2Teresa Ravizza
2Liliana Bernardino
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We investigated the consequences of transient application of specific stimuli mimicking inflammation to hippocampal tissue on microglia activation and neuronal cell vulnerability to a subsequent excitotoxic insult. Two-week-old organotypic hippocampal slice cultures, from 7-day-old C57BL/6 donor mice, were exposed for 3 h to lipopolysaccharide (LPS; 10(More)
  • Teresa Ravizza, Sian-Marie Lucas, Silvia Balosso, Liliana Bernardino, George Ku, Francesco Noé +4 others
  • 2006
PURPOSE Cytokines and related inflammatory mediators are rapidly synthesized in the brain during seizures. We previously found that intracerebral administration of interleukin-1 (IL-1)-beta has proconvulsant effects, whereas its endogenous receptor antagonist (IL-1Ra) mediates potent anticonvulsant actions in various models of limbic seizures. In this(More)
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