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Many semiconductor quantum devices utilize a novel tunneling transport mechanism that allows picosecond device switching speeds. The negative differential resistance characteristic of these devices, achieved due to resonant tunneling, is also ideally suited for the design of highly compact, self-latching logic circuits. As a result, quantum device(More)
The resonant tunneling diode (RTD) has been widely studied because of its importance in the field of nanoelectronic science and technology and its potential applications in very high speed/functionality devices and circuits. Even though much progress has been made in this regard, additional work is needed to realize the full potential of RTD's. As research(More)
BACKGROUND Coronary artery disease leading to myocardial ischemia is the most common cause of heart failure. Apelin (APLN), the endogenous peptide ligand of the APJ receptor, has emerged as a novel regulator of the cardiovascular system. METHODS AND RESULTS Here we show a critical role of APLN in myocardial infarction (MI) and ischemia-reperfusion (IR)(More)
First augmented circuit simulator version was named NDR SPICE (1994) and was added with simple mechanisms like forced convergence routine to recover from oscillatory (non-convergence) situations in DC simulation. The second version, named QSPICE (1999), was augmented with homotopy-based convergence routine, named RTD-stepping as well as a novel limiting(More)
Devices from three major groups of two-terminal devices, i.e., transit-time diodes, transferred-electron devices, and quantum-well devices, have been employed successfully to generate RF power at frequencies above 200 GHz. At frequencies up to 300 GHz, Si IMPATT diodes yielded the highest RF power levels from any fundamental solid-state source, e.g., 50 mW(More)
Failure of chemotherapy associated with expression of the multidrug resistance protein p170 frequently occurs in retinoblastoma (RB). Despite using cyclosporine, which inhibits p170 and improves our chemotherapy results, rare failures occur. In nonmetastatic primarily enucleated RBs, we show expression ofpl7O in 3 of 18 samples and expression of multidrug(More)
Angiotensin-converting enzyme inhibitors (ACE-I) and specific nonpeptide angiotensin II (ANG II) receptor antagonists have been used extensively to treat a variety of cardiovascular disorders in experimental animals and humans. Despite their widespread use, only a limited amount of data has been published regarding the effect that renin-angiotensin system(More)
The microvascular endothelium of the kidney glomerulus is injured in Shiga-like toxigenic bacterial infection, genetic or acquired loss of complement regulatory protein function, and allo-immune responses of solid-organ or bone marrow transplantation. Existing models of diseases with glomerular endothelial cell (EC) injury, collectively grouped as(More)
23 mm antenna), the two field components become comparable. For a 21 ϫ 21 mm antenna with the proposed type of slot, we found that the antenna generates left-hand circular polarization [9]. The 3-dB axial-ratio bandwidth obtained was 2.8%. The impedance bandwidth is much wider. Note that if the slots are reversed, right-hand circular polarization results(More)