George Heufelder

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Interleukin-1 (IL-1) plays an important role in the pathogenesis of Graves' ophthalmopathy (GO). Impaired antagonism of the proinflammatory cytokine IL-1 by the naturally occurring IL-1 receptor antagonist (IL-1RA) has been implicated in the initiation and perpetuation of various autoimmune diseases and may play a role in the evolution of GO. Cigarette(More)
The aim of this prospective, randomized study was to investigate the serum levels of tumor necrosis factor-alpha (TNF-alpha), soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular cell adhesion molecule-1 (sVCAM-1), and soluble interleukin-1 receptor antagonist (sIL-1RA) in patients with thyroid eye disease (TED) before and 1 and 3 months(More)
Foodborne illness presents a public health challenge in USA. There is an urgent need for the federal government and food industries to expand efforts to prevent any food contamination that potentially could be harmful to human health. The Food Safety Laboratory (FSL), ARS, USDA, is one of the leading laboratories for the development of optoelec-tronic(More)
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