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Escherichia coli fed-batch cultivations at 22 m3 scale were compared to corresponding laboratory scale processes and cultivations using a scale-down reactor furnished with a high-glucose concentration zone to mimic the conditions in a feed zone of the large bioreactor. Formate accumulated in the large reactor, indicating the existence of oxygen limitation(More)
Clustering is automated identification of groups of objects based on similarity. In clustering two major research issues are scalability and the requirement of domain knowledge to determine input parameters. Most approaches suggest the use of sampling to address the issue of scalability. However, sampling does not guarantee the best solution and can cause(More)
Experimental evaluation of a diffusion reaction model (part 1) for the determination of both steady-and transient-state behavior of biofilters for waste air biotreatment is presented. The model, applied to the aerobic biodegradation of methyl ethyl ketone (MEK) and methyl isobutyl ketone (MIBK) vapors from air as single and as mixed pollutants, proved(More)
The effects of changing operating conditions on the biooxidation of methyl ethyl and/or methyl isobutyl ketone in continuous flow enrichment culture are examined. Particular emphasis is placed on responses to step changes in feed stream concentrations and to substrate pulses injected directly into the culture supernatant. In general, the enrichment culture(More)
New data mining tools and algorithms are available for vertical data mining communities for scalable and efficient data mining to discover the hidden nuggets from huge repositories of data. Most of the traditional data mining algorithms do not scale on these huge datasets. This is due to insufficient computational resources, currently available on a single(More)
Image segmentation is a challenging task in image processing. The purpose is to divide up pixels into different partitions in which members of each partition have similar characteristics and a unique label. Image segmentation and extracting the characteristics of a tumor are powerful tools that can be used in medical science. In the case of breast cancer(More)