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This paper discusses the role of case studies in systems engineering and systems management , especially case studies that involve systems acquisition. We first provide a brief overview of case studies, including some of the analysis techniques useful for the conduct of case studies. Next, we discuss a two-dimensional framework for systems engineering and(More)
The adaptive response of vascular endothelial cells to shear stress alteration induced by global hemodynamic changes is an essential component of normal endothelial physiology in vivo; and an understanding of the transient regulation of endothelial phenotype during adaptation will advance our understanding of endothelial biology and yield new insights into(More)
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