George A. Jervis M. D.

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Although a relatively rare disease, amaurotic idiocy has attracted much attention because of its unique pathology, its characteristic genetic behavior, and, of late, its debated relationship to general disorders of fat metabolism. As is well known, four types of this disease are recognized, i. e., the infantile, late infantile, juvenile, and adult type.(More)
Two cases of Wilson's disease (progressive lenticular degeneration) are described from a clinical and pathologic point of view. In addition, the clinical features of a third case are reported. The first case showed the typical clinicopathologic picture of the disease, while the second case, although exhibiting characteristic clinical features and the(More)
The study of experimental intoxication still holds an important place in neuropathology. If the expectation of those early investigators, who tried to produce nerve cell lesions characteristic of each poison, has not been realized, interesting facts, however, have been acquired and promising leads indicated. Thus, it seems now to be recognized that the(More)
Nine chimpanzees were fed the TN strain of rodent-adapted poliomyelitis virus. All developed homotypic antibodies and two became intestinal carriers of the virus. None showed clinical signs of disease. Subsequent oral challenge with Brunhilde virus caused viremia and paralysis in one control chimpanzee and intestinal carriage in all other control animals(More)
The study of the problem of the effects of insulin upon the central nervous system has received new impetus since the application of Sakel's method to the treatment of schizophrenia. Although symptoms related to the central nervous system have a prominent part in the clinical picture of hyperinsulinism, the nature of the underlying brain pathology is still(More)
The term Pick's disease is used to denote a specific type of progressive dementia occurring in the presenile age period characterized pathologically by circumscribed atrophy of the cerebral cortex. This condition was first described by A. Pick in 1892 and to date over two hundred cases have been reported in the medical literature. The clinical and(More)
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