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The peripheral astrocyte process (PAP) preferentially associates with the synapse. The PAP, which is not found around every synapse, extends to or withdraws from it in an activity-dependent manner. Although the pre- and postsynaptic elements have been described in great molecular detail, relatively little is known about the PAP because of its difficult(More)
Amongst several forms of glia-neuronal communication, glia-synaptic interaction appears particularly interesting in the light of the well-known examples of two-way signaling between neurons and astrocytes. We review recent structural and physiological evidence showing that the structural correlate of glia-synaptic interaction is the peripheral astrocyte(More)
Astrocytes in vivo extend thin processes termed peripheral astrocyte processes (PAPs), in particular around synapses where they can mediate glia-neuronal communication. The relation of PAPs to synapses is not based on coincidence, but it is not clear which stimuli and mechanisms lead to their formation and are active during process extension/ retraction in(More)
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