Geoffrey Wu

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OBJECTIVE To compare the functional performance of subjects with unilateral anterior cruciate ligament (ACL) reconstruction. DESIGN Cross-sectional comparative clinical trial. SETTING A physical therapy outpatient department. SUBJECTS Thirty-one subjects with unilateral ACL reconstruction for more than 5 months. INTERVENTION Patients under 3 bracing(More)
The purpose of this study was to use QbD approaches to evaluate the effect of several variables and their interactions on quality of a challenging model murine IgG3κ monoclonal antibody (mAb), and then to obtain an optimized formulation with predefined quality target product profile. This antibody was chosen because it has a propensity to precipitate and(More)
The sensorimotor performance of the knee joint in 31 subjects who had undergone unilateral anterior cruciate ligament reconstruction at least 5 months previously was tested under three bracing conditions, 1) the DonJoy Legend brace, 2) a mechanical placebo brace, and 3) no brace, in random order. The accuracy of the subjects' ability to reproduce specified(More)
The development of multi-shelled hollow carbonate nanospheres (MHCN) for biomedical applications is challenging, and has not been reported. In this study, a facile approach is firstly reported to synthesize hierarchically porous MHCN with controllable shell numbers using a novel strategy called layer-by-layer thermal decomposition of organic acid salts and(More)
Lawrence X. Yu, Ilgaz Akseli, Barbara Allen, Gregory Amidon, Tara Gooen Bizjak, Ashley Boam, Margaret Caulk, David Doleski, Joseph Famulare, Adam C. Fisher, Scott Furness, Brian Hasselbalch, Henry Havel, Stephen W. Hoag, Robert Iser, Bruce D. Johnson, Robert Ju, Paula Katz, Emanuela Lacana, Sau L. Lee, Richard Lostritto, Grace McNally, Mehul Mehta,(More)
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