Geoffrey Thomas

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In Nature, protein capsids function as molecular containers for a wide variety of molecular cargoes. Such containers have great potential for applications in nanotechnology, which often require encapsulation of non-native guest molecules. Charge complementarity represents a potentially powerful strategy for engineering novel encapsulation systems. In an(More)
Malate synthase, one of the two enzymes unique to the glyoxylate cycle, is found in all three domains of life, and is crucial to the utilization of two-carbon compounds for net biosynthetic pathways such as gluconeogenesis. In addition to the main isoforms A and G, so named because of their differential expression in E. coli grown on either acetate or(More)
In this paper, we question the common practice of assigning security impact ratings to OS updates. Specifically, we present evidence that ranking updates by their perceived security importance, in order to defer applying some updates, exposes systems to significant risk. We argue that OS vendors and security groups should not focus on security updates to(More)
Malate synthases found in cells of the halophilic Archaea constitute a third isoform of this important metabolic enzyme, in addition to the well characterized A and G isoforms. They share little sequence similarity with these other two isoforms. Database searches using basic local alignments reveal relationships between isoforms A and G, but do not indicate(More)
In my work, I am most interested in exploring themes of human connection. These explorations are often filtered through the culture of technology. I am increasingly influenced by the destabilizing elements of digital media. In my work, I hope to find ways to unravel the control of traditional narratives, adopt nonlinear and nonhierarchical structures,(More)
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