Geoffrey Solano

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An oligonucleotide-specific capture plate hybridization assay has been developed to rapidly, specifically, and sensitively detect Haemophilus parasuis from nasal swabs. Several in vitro studies have been performed to determine the sensitivity and specificity of the test, and in vivo studies have validated this technique in pigs. Results suggest that the(More)
An avidin-biotin complex immunohistochemistry technique was developed to detect Haemophilus parasuis serovar 5 in experimentally infected 18-21-day-old conventional pigs, using a rabbit polyclonal antiserum. Seven of 10 intratracheally inoculated animals developed a low to medium degree of fibrinous polyserositis; meninges and pleura were the most severely(More)
Lung cancer is one of the deadliest types of cancer around the world. Epidemiologic studies have shown that genetic variability is among the factors that affect a person's susceptibility to lung cancer. A recent study conducted by a team of researchers from the United States National Cancer Institute among 14,000 Asian women found out that Asian women,(More)
The interaction of bacteria and virus has been well demonstrated in the pathogenesis of respiratory disease in swine. The interaction between porcine respiratory and reproductive syndrome virus (PRRSv) and Haemophilus parasuis has not been studied. We initiated studies to evaluate a possible effect of the PRRSv on the pathogenesis of polyserositis caused by(More)
Porcine reproductive and respiratory syndrome virus (PRRSV) infection in young piglets is frequently associated with secondary infection due to various pathogens, especially those of the respiratory tract. One of the most important mechanisms in respiratory diseases is related to the alteration of function of porcine alveolar macrophages (PAMs). The(More)
Lung cancer is one of the most fatal types of cancer around the world. The World Cancer Research Fund International estimated that in 2012, 1.8 million new cases of this disease were diagnosed. Early diagnosis and classification of this condition prompts medical professionals on safer and more effective treatment of the patient. Availability of microarray(More)
Two experiments were designed to study ultrastructural changes in porcine alveolar macrophages (PAM) inoculated with porcine reproductive and respiratory syndrome (PRRS) virus (experiment 1) and with PRRS virus and Haemophilus parasuis (experiment 2). In both experiments, the viral infectious dose represented a "multiplicity of infection" of 1. Viral(More)
Immunohistochemical, viral and bacterial isolation techniques were used to study the distribution and localization of porcine reproductive and respiratory syndrome virus (PRRSV) and Haemophilus (H.) parasuis in experimentally infected pigs. Thirty pigs seronegative to PRRSV and H. parasuis were divided into four groups. Group A pigs (10 animals) were(More)
Microarray is one of the technologies used in the interdisciplinary science of Biolnformatics. Its primary objective is to discover biological knowledge among genes through their expressions. Gene expressions usually come in large and multidimensional data which makes computational and statistical analyses necessary. Clustering of microarray data is one of(More)
Radiolarian assemblages have played a significant role as a biostratigraphic and paleoenvironmental tool used in the geological settings. These species can be used in studying sediments lacking calcareous fossils. Easy identification of these species would allow micropaleontologists to proceed further into studying the structure and way of living of these(More)