BACKGROUND The disease burden of influenza infection among children is not well established. We conducted a population-based surveillance of medical visits associated with laboratory-confirmed influenza. METHODS Eligible children were younger than five years of age, resided in three U.S. counties, and had a medical visit for an acute respiratory tract… (More)
Recent studies have associated human metapneu-movirus (HMPV) infection in children with respiratory disease of similar severity as respiratory syncytial virus (RSV) infection. We studied 668 banked swab specimens (one per admission) collected from a population-based, prospective study of acute respiratory illness among inpatient children from two U.S.… (More)
Accessed (insert date) [include page numbers, table number, etc. if applicable] It is emphasized that concepts relevant to HIV management evolve rapidly. The Panel has a mechanism to update recommendations on a regular basis, and the most recent information is available on the AIDSinfo Web site (http://aidsinfo.nih.gov). Advisory Council).
Methods Persons included in the study were enrolled as New Vaccine Surveillance Network study participants (n = 1,897) and had a fecal specimen collected (n = 1,363, 72%) that was tested for norovirus and rotavirus (n = 1,295, 95%) (Technical Appendix Figure 1). Pentavalent rotavirus vaccine (RV5) for routine use in US infants in February 2006 in children… (More)
Surveillance for rotavirus-associated diarrhea after implementation of rotavirus vaccination can assess vaccine effectiveness and identify disease-associated genotypes. During active vaccine postlicensure surveillance in the United States, we found a novel rotavirus genotype, G14P, in a stool sample from a child who had diarrhea. Unusual rotavirus… (More)
To describe the process and assess outcomes for the first 2 years of newborn screening for severe combined immunodeficiency (SCID NBS) in New York State (NYS). The NYS algorithm utilizes a first-tier molecular screen for TRECs (T-cell receptor excision circles), the absence of which is indicative of increased risk of immunodeficiency. During the first 2… (More)
We compared rotavirus detection rates in children with acute gastroenteritis (AGE) and in healthy controls using enzyme immunoassays (EIAs) and semiquantitative real-time reverse transcription PCR (qRT-PCR). We calculated rotavirus vaccine effectiveness using different laboratory-based case definitions to determine which best identified the proportion of… (More)