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  • Peter M. Bowers, Tamlyn Y. Neben, +11 authors David John King
  • Biology, Medicine
  • The Journal of biological chemistry
  • 15 March 2013
  • A method for simultaneous humanization and affinity maturation of monoclonal antibodies has been developed using heavy chain complementarity-determining region (CDR) 3 grafting combined with somaticContinue Reading
  • Robert A. Horlick, John L. Macomber, +6 authors David John King
  • Biology, Medicine
  • The Journal of biological chemistry
  • 5 July 2013
  • A mammalian expression system has been developed that permits simultaneous cell surface display and secretion of the same protein through alternate splicing of pre-mRNA. This enables a flexibleContinue Reading