Geoff W. Barton

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Measuring the properties of endogenous cell proteins, such as expression level, subcellular localization, and turnover rates, on a whole proteome level remains a major challenge in the postgenome era. Quantitative methods for measuring mRNA expression do not reliably predict corresponding protein levels and provide little or no information on other protein(More)
A novel and highly versatile doping method has been developed to allow active dopants, including materials incompatible with the polymer matrix, to be incorporated into microstructured polymer optical fibers through the use of nanoparticles. The incorporation of quantum dots and silica nanoparticles containing Rhodamine isothiocyanate is demonstrated.
A nonlinear model of a recombinant Escherichia coli producing porcine growth hormone (pGH) fermentation was developed. The model was used to calculate a glucose feeding and temperature strategy to optimize the production of pGH. Simulations showed that the implementation of optimal feed and temperature profiles was sensitive to the maximum specific growth(More)
A methodology is presented suitable for the fabrication of a wide range of microstructured polymer optical fibres (mPOFs), a recent development where light guidance is achieved through the incorporation of a pattern of air channels that run the entire length of the fibre. We show that the key to good mPOF fabrication is a secondary draw oven that has tight(More)
Educational hypermedia offers flexible access to information, supports convenient learning styles, and provides a number of teaching advantages. The student’s desire to learn can be enhanced by involving them in the education process and by presenting the course material in an attractive manner to encourage student participation. A well-implemented(More)
We successfully used CdSe/ZnS quantum dots (QDs) as a dopant within a polymethylmethacrylate (PMMA) matrix. This doped material was used in the fabrication of a microstructured polymer optical fiber whose photoluminescence was characterized. A detailed analysis of the emission properties of the QDs as a function of temperature is presented, with the(More)
Recent progress in microstructured polymer optical fibre fabrication and characterisation will be presented. A wide range of different optical functionalities can now be obtained by modifications of the microstructure, as is demonstrated by the fibres presented here. Microstructured fibres that are single-mode, highly birefringent or show twin-core coupling(More)
Electrocoagulation removes pollutant material from water by a combination of coagulant delivered from a sacrificial aluminium anode and hydrogen bubbles evolved at an inert cathode. Rates of clay particle flotation and settling were experimentally determined in a 7 L batch reactor over a range of currents (0.25-2.0 A) and pollutant loadings (0.1-1.7 g/L).(More)