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Frailty syndrome: an overview
TLDR
Frailty is a common and important geriatric syndrome characterized by age-associated declines in physiologic reserve and function across multiorgan systems, leading to increased vulnerability for adverse health outcomes, including obesity and specific diseases.
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The Salutary Influence of Forest Bathing on Elderly Patients with Chronic Heart Failure
TLDR
Results provided direct evidence that forest bathing has a beneficial effect on CHF patients, and thus may pave the way for potential development of forest bathing as an effective adjunctive therapy on cardiovascular disorders.
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Protective effects of allicin on streptozotocin-induced diabetic nephropathy in rats.
TLDR
Treatment with allicin for 12 weeks ameliorated diabetes-induced morphological alterations of the kidney and decreased FBG, BUN, sCr, triglyceride (TG) and 24 h UAE in diabetic rats, suggesting thatallicin may play a protective role in diabetic nephropathy via the TGF-β1/ERK pathway in diabetic Rats.
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Adjunctive Therapeutic Effects of Cinnamomum Camphora Forest Environment on Elderly Patients with Hypertension
TLDR
Camphora environment significantly decreased the DBP and inflammatory level, balanced the autonomic activity and improved the mood state of participates, which might be associated with the biological effectiveness of terpenes, implying that C. camphora forest environment might be an adjunctive therapy for HTN patients.
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Effect of high-intensity interval training on cardiac structure and function in rats with acute myocardial infarct.
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Sargassum fusiforme fucoidan alleviates diet-induced insulin resistance by inhibiting colon-derived ceramide biosynthesis.
TLDR
The results suggested that SFF increased TudCA levels by remodeling gut microbiota, and TUDCA, a natural FXR antagonist, inhibited the FXR/SHP signaling pathway to reduce colon-derived biosynthesis of ceramide, thereby improving insulin resistance in the diet-induced obese mice.
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Berberine diminishes cancer cell PD-L1 expression and facilitates antitumor immunity via inhibiting the deubiquitination activity of CSN5
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Hepatoprotection of Berberine Against Hydrogen Peroxide‐induced Apoptosis by Upregulation of Sirtuin 1
TLDR
It is demonstrated that the protective effect of B BR against H2O2‐induced apoptosis was associated with regulation of SIRT1 in hepatic cell line L02, which provided a possible explanation for its antioxidant activity, and implied an application of BBR for the therapeutic relevance in oxidative‐stress‐related liver diseases.
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Long non‐coding RNAs in aging organs and tissues
TLDR
Some examples of known and novel lncRNAs that have been implicated in the aging process in the whole mammalian body are summarized and these patterns, conservation and characters during aging are discussed to further promote the development of research on lnc RNAs and the Aging process.
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Suppressive effects of sirtinol on human cytomegalovirus (hCMV) infection and hCMV-induced activation of molecular mechanisms of senescence and production of reactive oxygen species
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