Gennadiy Novitskiy

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A large group of viruses rely on low pH to activate their fusion proteins that merge the viral envelope with an endosomal membrane, releasing the viral nucleocapsid. A critical barrier to understanding these events has been the lack of approaches to study virus-cell membrane fusion within acidic endosomes, the natural sites of virus nucleocapsid capsid(More)
— Aims: Increased plasma tumour necrosis α (TNFα) and elevated monocyte nuclear factor kappa B (NF-κB) are associated with liver injury and inflammation in models of alcoholic liver disease and are found to be elevated in monocytes of patients with alcoholic hepatitis. Acetaldehyde enhances, whereas TNFα inhibits, transcription of the type I collagen(More)
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