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The capacity of human adipose-derived stem cells (hADSCs) to differentiate into motor neurons and the identity of molecular factors that confer hADSCs with the competence of motor neurons have yet to be elucidated. Here, retinoic acid and sonic hedgehog were applied to examine whether hADSCs could be differentiated into motor neurons. As early as 6 h after(More)
BACKGROUND Tubeimoside-1 (TBMS1) is a natural compound isolated from tubeimoside, which has been widely used as a traditional Chinese herbal medicine. The purpose of the present study is to investigate the anti-tumor effect and the underling mechanism of TBMS1 on glioma cancer cells. METHODS The MTT assay was performed to evaluate the effect of TBMS1 on(More)
The genome of linear double-stranded DNA (dsDNA) viruses is packaged into a preformed procapsid fueled by ATP hydrolysis. The central channel component of the bacteriophage phi29 motor is a connector protein, which has been successfully inserted into a lipid bilayer and exhibited robust capability for extremely reliable and precise assessment of the(More)
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