Genevieve M Matanoski

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A cohort of 12,110 male workers employed 1 or more years in eight styrene-butadiene polymer (SBR) manufacturing plants in the United States and Canada has been followed for mortality over a 40-year period, 1943 to 1982. The all-cause mortality of these workers was low [standardized mortality ratio (SMR) = 0.81] compared to that of the general population.(More)
The authors investigated the effect of charcoal smoke exposure on risks of acute upper and lower respiratory infection (AURI and ALRI) among children under age 18 months in Santo Domingo, Dominican Republic (1991-1992). Children living in households using charcoal for cooking (exposed, n = 201) were age-matched to children living in households using propane(More)
Asthma prevalence in the Cataño Air Basin of Puerto Rico is 27% for children aged 13-14 years and 45% for children aged 5-6 years. There is concern that these rates are related to air pollution. The authors conducted a nested case-control study to evaluate whether proximity to air pollution point sources was associated with increased risk of asthma attacks.(More)
The U.S. Environmental Protection Agency (U.S. EPA) classifies dichloromethane (DCM) as a "probable human carcinogen," based upon its risk assessment conducted in the late 1980s (http://www.epa.gov/iris/subst/0070.htm). Since that time, cancer risk-assessment practices have evolved, leading to improved scientifically based methods for estimating risk and(More)
A population from a hearing clinic in Washington County, Maryland, in 1943-1960 was followed to assess the risk of developing neoplasms from radium treatment of the nasopharynx for adenoid hypertrophy. Of the 2,925 subjects who attended the clinic, 904 received radium treatment. A nonconcurrent prospective study compared the cancer incidence among the(More)
Epidemiologic studies have consistently reported increased daily mortality and hospital admissions for ischemic heart disease related to daily changes in ambient particulate levels. One theory is that substances adhering to particulates might have a cardiovascular effect. Styrene has been found in very low doses in air and has chemical characteristics that(More)
A Toxicological Profile for 1,3-Butadiene, Draft for Public Comment was released in September 2009. This edition supersedes any previously released draft or final profile. Toxicological profiles are revised and republished as necessary. For information regarding the update status of previously released profiles, contact ATSDR at: FOREWORD This toxicological(More)