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Multireader multicase (MRMC) variance analysis has become widely utilized to analyze observer studies for which the summary measure is the area under the receiver operating characteristic (ROC) curve. We extend MRMC variance analysis to binary data and also to generic study designs in which every reader may not interpret every case. A subset of the(More)
In most cases authors are permitted to post their version of the article (e.g. in Word or Tex form) to their personal website or institutional repository. Authors requiring further information regarding Elsevier's archiving and manuscript policies are encouraged to visit: Keywords: Uncertainty Training variability Microarray classification Area under the(More)
Commonly used methods for depicting geographic variation in cancer rates are based on rankings. They identify where the rates are high and low but do not indicate the magnitude of the rates nor their variability. Yet such measures of variability may be useful in suggesting which types of cancer warrant further analytic studies of localized risk factors. We(More)
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