Gemunu H. Gunaratne

4Benjamin Soibam
3Jason Shulman
3Lars Seemann
2Scott D. Pletcher
Learn More
Drosophila adults, when placed into a novel open-field arena, initially exhibit an elevated level of activity followed by a reduced stable level of spontaneous activity and spend a majority of time near the arena edge, executing motions along the walls. In order to determine the environmental features that are responsible for the initial high activity and(More)
We use Karhunen–Loeve ͑KL͒ decomposition of video images from an experiment to analyze a spatiotemporal dynamic state, unique to cellular flames, referred to as a ''hopping state.'' Ordered states of cellular flames on a circular burner consist of one or two concentric rings of luminous cells. The hopping states correspond to the motions of individual cells(More)
Inner porous regions play a critical role in the load bearing capability of large bones. We show that an extension of disordered elastic networks [Chung et. al., Phys. Rev. B, 54, 15094 (1996)] exhibits analogs of several known mechanical features of bone. The " stress-backbones " and histograms of stress distributions for healthy and weak networks are(More)
  • Benjamin Soibam, Rachel L. Goldfeder, Claire Manson-Bishop, Rachel Gamblin, Scott D. Pletcher, Shishir Shah +2 others
  • 2012
In open field arenas, Drosophila adults exhibit a preference for arena boundaries over internal walls and open regions. Herein, we investigate the nature of this preference using phenomenological modeling of locomotion to determine whether local arena features and constraints on movement alone are sufficient to drive positional preferences within open field(More)
We study the arrangements of recurved bristles on the anterior wing margin of wild-type and mutant Drosophila. The epidermal or neural fate of a proneural cell depends on the concentrations of proteins of the achaete-scute complex. At puparium formation, concentrations of proteins are nearly identical in all cells of the anterior wing and each cell has the(More)
In a seminal paper in 1973, Black and Scholes argued how expected distributions of stock prices can be used to price options. Their model assumed a directed random motion for the returns and consequently a lognormal distribution of asset prices after a finite time. We point out two problems with their formulation. First, we show that the option valuation is(More)
Control of complex processes is a major goal of network analyses. Most approaches to control nonlinearly coupled systems require the network topology and/or network dynamics. Unfortunately, neither the full set of participating nodes nor the network topology is known for many important systems. On the other hand, system responses to perturbations are often(More)
Habituation is a common form of non-associative learning in which the organism gradually decreases its response to repeated stimuli. The decrease in exploratory activity of many animal species during exposure to a novel open field arena is a widely studied habituation paradigm. However, a theoretical framework to quantify how the novelty of the arena is(More)
Early and accurate diagnoses of cancer can significantly improve the design of personalized therapy and enhance the success of therapeutic interventions. Histopathological approaches, which rely on microscopic examinations of malignant tissue, are not conducive to timely diagnoses. High throughput genomics offers a possible new classification of cancer(More)