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A comparative kinetic study in B6C3F1 mice, Osborne-Mendel (OM) and Sprague-Dawley (SD) rats has been undertaken with the major aim to determine the extent of covalent binding of chloroform reactive metabolites produced in vivo through oxidative and/or reductive metabolism in the target organs of chloroform carcinogenicity. Some additional kinetic(More)
Department of Microbiology, University of Leeds, Leeds LS2 9JT, UK Incubation of Aspergillus fumigatus NCPF 2140 in growth medium containing 1 O/ O chitin as sole carbon source led to induction of specific extracellular chitinolytic activity of 1-5 pmol GlcNAc released min'l (mg protein)'l. The effect was repressed by the inclusion of GlcNAc in the medium,(More)
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