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BACKGROUND Psychiatric and behavioural symptoms in dementia are associated with a range of negative outcomes, including institutional placement and the widespread use of psychotropic drugs in spite of limited evidence for their efficacy. AIMS To determine the prevalence of psychiatric and behavioural symptoms and the pattern of psychotropic drug(More)
BACKGROUND/AIMS To evaluate the efficacy of oxcarbazepine (OXC) in the treatment of agitation and aggression in patients with Alzheimer's disease, vascular dementia or both. METHODS This is an 8-week, multicenter, randomized, double-blind, placebo-controlled trial carried out independently of the pharmaceutical industry. Changes in the agitation and(More)
BACKGROUND Depression among patients in nursing homes is frequent and apparently underdiagnosed. Because depression is associated with negative outcomes, identification of groups at risk would improve the diagnosis and potentially improve the prognosis. AIM To confirm or reject the hypothesis that depression in nursing homes is associated with worse(More)
BACKGROUND Psychiatric symptoms and behavioral disturbances are highly prevalent in the residents of nursing homes. The Neuropsychiatric Inventory (NPI) is a commonly used scale for the assessment of such symptoms in diverse settings. We have conducted a study of the reliability and the validity of the Norwegian version of the NPI nursing home version(More)
BACKGROUND Pain is frequent and distressing in people with dementia, but no randomized controlled trials have evaluated the effect of analgesic treatment on pain intensity as a key outcome. METHODS Three hundred fifty-two people with dementia and significant agitation from 60 nursing home units were included in this study. These units, representing 18(More)
BACKGROUND The aims of the study were to examine the validity of the MADRS and to compare it with the validity of the Cornell Scale for Depression in Dementia (CSDD). METHODS We included 140 patients without dementia, with mean age 81.5 (sd 7.7) years. Trained psychiatric nurses interviewed all of them using the MADRS. In addition, for 70 patients(More)
AIM The present study describes the quality of life (QOL) and explores health-related factors associated with domains of the QOL in the acutely ill and hospitalised elderly. METHOD In all, 484 elderly (65-101 years, 241 men) patients hospitalised in an acute medical unit participated. Their QOL (in its overall and physical, psychological, social and(More)
OBJECTIVE This study investigates the natural course of neuropsychiatric symptoms and the concomitant use of psychotropic medication among a large and representative sample of nursing-home patients with dementia. METHOD The authors performed two data collections with structured interviews in a 1-year follow-up cohort-study including 26 nursing homes in(More)
BACKGROUND Psychotropic drugs are extensively prescribed for the treatment of neuropsychiatric symptoms, despite modest efficacy and severe side effects. AIMS We examined trends in psychotropic drug prescribing in Norwegian nursing homes from 1997 to 2009, in order to gain insight in practice development. METHODS The study is a secondary data analysis(More)
BACKGROUND AND AIMS The purpose of our study was to examine whether severity of dementia, behavioral and psychological symptoms and depression can predict falls among nursing home residents, such as demographic variables, activities of daily living, and use of psychotropic drugs, when potential confounders are controlled for. METHODS 1147 nursing home(More)