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Systemic Lupus Erythematosus (SLE) is a chronic, systemic autoimmune disease characterized by loss of tolerance to self-antigens. Regulatory T cells (T(REG)) are those CD4+ T cells that constitutively express high levels of CD25 and exhibit powerful suppressive properties. The aim of this work was to quantify CD4+CD25+ (T(REG)) cells and the Mean(More)
BACKGROUND The identification of additional genetic risk factor is an on-going process that will aid in the understanding of rheumatoid arthritis (RA) aetiology. A genome-wide association scan in Crohn's (CD) disease highlighted the interleukin-23 receptor (IL23R) gene as a susceptibility factor. Since the IL-23/IL-17 pathway is known to associate with(More)
OBJECTIVES We aimed to compare serum levels of interleukin-6, visfatin, and hyaluronic acid in chronic hepatitis C Egyptian patients who received standard of care (SOC) therapy for chronic hepatitis C virus (HCV) consisting of pegylated interferon (PEG-IFN) and ribavirin (RBV) and in those who received SOC with vitamin D (vit D) for 48 weeks in HCV genotype(More)
Abbreviations: Hp, haptoglobin; CAD, coronary artery disease; DM, diabetes mellitus; CRP, serum C-reactive protein; PCR, polymerase chain reaction; ECG, electro-cardiograph; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBS, fasting blood sugar; 2hsBS, 2 hours postprandial blood glucose; HbA1c, glycated hemoglobin; TC, total cholesterol; TG,(More)
Juvenile idiopathic arthritis (JIA) is an autoimmune diseases characterized by chronic arthritis and systemic manifestations. Autoimmune diseases can affect the upper airways including the larynx. The aim of this study was to investigate laryngeal involvement in JIA patients and its possible association with JIA disease parameters. Fifty consecutive JIA(More)
BACKGROUND Vitamin D deficiency is a prevalent condition among critically ill patients. Information about the relationship between vitamin D levels and outcomes in the intensive care unit (ICU) is sparse. PURPOSE To evaluate vitamin D status among critically ill patients and its relevance to severity of illness, ICU stay period, and mortality. METHODS(More)
To evaluate the clinical utility of serum levels of N-terminal pro C-type natruretic pep-tide (NT-pro CNP) in patients with hepatitis C related chronic liver disease (CLD), in prospective to disease complications and progression. This study included 66 hepatitis C-related CLD patients with and without ascites and 15 healthy individuals (control group).(More)
Volume 17, No.1, April 2010 The Gulf Journal of Dermatology and Venereology INTRODUCTION Leprosy is a chronic granulomatous disease principally affecting the skin and peripheral nervous system. It exhibits a wide spectrum of presentation. Erythema nodosum leprosum (ENL) is an inflammatory complication of leprosy that results in painful skin lesions on the(More)
Background and aims: Heme oxygenase-1 (HO-1), the rate limiting enzyme in heme catabolism and its three by-products have recently received overwhelming research attention because of their anti-inflammatory and cytoprotective effects. Gene expression of HO-1 is upregulated in response to various oxidative stress stimuli. Patients with non alcoholic fatty(More)
C.difficile is an important cause of nosocomial diarrhoea and pseudomembranous colitis (PMC), has a mortality rate that ranges from 15 to 30%. Therefore, in this study we investigated the incidence rate, toxigenicity and susceptibility pattern of C.difficile isolates to anti-anaerobic agents. We have also investigated the genotypes of clinical isolates by(More)
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