Learn More
BACKGROUND Stress is associated with an increased incidence of cardiovascular disease. The impact of chronic stress on cardiovascular risk has been studied by measuring cortisol in serum and saliva, which are measurements of only 1 time point. These studies yielded inconclusive results. The measurement of cortisol in scalp hair is a novel method that(More)
STUDY DESIGN A systematic review of the literature. OBJECTIVES To assess the efficacy of conservative treatment in patients with whiplash injuries. SUMMARY OF BACKGROUND DATA Many treatments are available for patients with whiplash injury, but there continues to be no evidence for their accepted use. METHODS A computerized literature search of(More)
BACKGROUND Falls occur frequently in older people and strongly affect quality of life. Guidelines recommend multifactorial, targeted fall prevention. We evaluated the effectiveness of a multifactorial intervention in older persons with a high risk of recurrent falls. METHODS A randomized controlled trial was conducted from April 3, 2005, to July 21, 2008,(More)
UNLABELLED The validity of self-reported osteoporosis is often questioned, but validation studies are lacking. We validated self-reported prevalence and incidence of osteoporosis against self-reported and administrative data on medications. The concurrent validity was moderate to good for self-reported prevalent osteoporosis, but only poor to moderate for(More)
OBJECTIVE Hypercortisolism is associated with muscle weakness. This study examines the relationship between cortisol and physical performance in older persons. DESIGN/PATIENTS The study was conducted within the Longitudinal Aging Study Amsterdam (LASA), an ongoing cohort study in a population-based sample of healthy older persons in the Netherlands. Data(More)
BACKGROUND Associations of sitting-time and physical activity with depression are unclear. PURPOSE To examine concurrent and prospective associations between both sitting-time and physical activity with prevalent depressive symptoms in mid-aged Australian women. METHODS Data were from 8950 women, aged 50-55 years in 2001, who completed mail surveys in(More)
BACKGROUND This study explored the associations between various types of activities, their underlying physical components, and recurrent falling in community-dwelling older persons. METHODS This study included 1,329 community-dwelling persons (>or=65 years) of the Longitudinal Aging Study Amsterdam (LASA). The time spent in walking, cycling, light and(More)
BACKGROUND The European Project on OSteoArthritis (EPOSA), here presented for the first time, is a collaborative study involving five European cohort studies on aging. This project focuses on the personal and societal burden and its determinants of osteoarthritis (OA). The aim of the current report is to describe the purpose of the project, the post(More)
CONTEXT High cortisol level is known to be associated with osteoporosis, hypertension, diabetes mellitus (DM), susceptibility to infections and depression and may protect against chronic obstructive pulmonary disease. OBJECTIVE This study assesses the association between cortisol level, 6- to 7.5-year mortality risk and prevalence of chronic diseases. (More)
UNLABELLED This study tests whether the relationship between physical activity and (recurrent) falling is U-shaped. Among 1,337 community-dwelling older persons, no evidence for a nonlinear association was found. If all older persons increase their physical activity level with 100 units, 4% may be prevented to become recurrent fallers. INTRODUCTION(More)