Geertruida H. de Bock

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Purpose: Presence of pelvic lymph node metastases is the main prognostic factor in early-stage cervical cancer patients, primarily treated with surgery. Aim of this study was to identify cellular tumor pathways associated with pelvic lymph node metastasis in early-stage cervical cancer. Experimental Design: Gene expression profiles (Affymetrix U133 plus(More)
The purpose of the study was to analyse the needs of women who participated in a routine follow-up programme after treatment for primary breast cancer. A cross-sectional survey was conducted using a postal questionnaire among women without any sign of relapse during the routine follow-up period. The questionnaire was sent 2-4 years after primary surgical(More)
BACKGROUND The present paper is a first evaluation of the use of "CEAwatch", a clinical support software system for surgeons for the follow-up of colorectal cancer (CRC) patients. This system gathers Carcino-Embryonic Antigen (CEA) values and automatically returns a recommendation based on the latest values. METHODS Consecutive patients receiving(More)
Thus far, studies investigating the differences in tumour characteristics between breast cancer in BRCA1-carriers and other patients, have focused on highly selected groups of patients, potentially limiting the conclusions that can be drawn. Previously, we had identified 10 patients with BRCA1 germline mutations in a hospital-based series of 642 breast(More)
B reast cancer is a common disease in women. The lifetime risk of breast cancer is about 1 in 12 in the UK, 1 in 10 in The Netherlands, and 1 in 8 in the USA. 1 The majority of women are affected in the peri-or postmenopausal years: about 75% of all breast cancer cases are diagnosed after the age of 50. 2 In western countries about 5 to 10% of breast cancer(More)
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