Ge Jin

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Natural disasters, such as hurricanes, tsunamis and earthquakes cause huge loss of life, enormous amounts of property damage, and lengthy recovery times. Although it is impossible to avoid the costs of disasters, human sufferings can be minimized through effective disaster management and decision support system that can facilitate and expedite the resource(More)
BACKGROUND Tumor-associated macrophages (TAMs) constitute a significant part of infiltrating inflammatory cells that are frequently correlated with progression and poor prognosis of a variety of cancers. Tumor cell-produced human beta-defensin-3 (hBD-3) has been associated with TAM trafficking in oral cancer; however, its involvement in tumor-related(More)
The purpose of our project is to develop an image guided system for the medialization laryngoplasty. One of the fundamental challenges in our system is to accurately register the preoperative 3D CT data to the intraoperative 3D surfaces of the patient. In this paper, we will present a combined surface and fiducial based registration method to register the(More)
  • Bin Yang, Cong Tian, Zhi-guang Zhang, Feng-chan Han, Rami Azem, Heping Yu +4 others
  • 2011
Craniofacial defects that occur through gene mutation during development increase vulnerability to eustachian tube dysfunction. These defects can lead to an increased incidence of otitis media. We examined the effects of a mutation in the Sh3pxd2b gene (Sh3pxd2b(nee)) on the progression of otitis media and hearing impairment at various developmental stages.(More)
Rapidly evolving research examining the extended role of human beta-defensins (hBDs) in chemoattraction, innate immune-mediated response, and promotion of angiogenesis suggest that the collective effects of hBDs extend well beyond their antimicrobial mechanism(s). Indeed, the numerous basic cellular functions associated with hBDs demonstrate that these(More)
The medialization laryngoplasty is a surgical procedure to improve the voice function of the patient with vocal fold paresis and paralysis. An image guided system for the medialization laryngoplasty will help the surgeons to accurately place the implant and thus reduce the failure rates of the surgery. One of the fundamental challenges in image guided(More)
BACKGROUND Macrophages are one of the major cell types in innate immunity against microbial infection. It is believed that the expression of proinflammatory genes such as tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6, and cyclooxygenase-2 (Cox-2) by macrophages is also crucial for activation of both innate and adaptive immunities. RNase L is an(More)
Xanthoceraside, a novel triterpenoid saponin extracted from the fruit husks of Xanthoceras sorbifolia Bunge, reverses cognitive deficits in intracerebroventricular injection of Aβ25–35 or Aβ1–42 mice. However, whether xanthoceraside has a positive effect on hyperphosphorylated tau protein remains unclear. We investigated the effects of xanthoceraside on(More)