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BACKGROUND Striae gravidarum (stretch marks developing during pregnancy) occur in 50% to 90% of women. They appear as red or purple lines or streaks that fade slowly to leave pale lines or marks on the skin. The abdomen, breasts and thighs are commonly affected. The exact cause of stretch marks is unclear and no preparation has yet been shown to be(More)
Deep fiber deployments for ultrafast broadband are both technically and economically challenging. Fixed access network sharing (FANS) offers a highly enhanced form of virtual unbundling of broadband access networks, enabling cost sharing and the dynamics of a competitive landscape. Data, control, and management interfaces are automated and harmonized among(More)
Cortactin (CTTN), first identified as a major substrate of the Src tyrosine kinase, actively participates in branching F-actin assembly and in cell motility and invasion. CTTN gene is amplified and its protein is overexpressed in several types of cancer. The phosphorylated form of cortactin (pTyr(421)) is required for cancer cell motility and invasion. In(More)
Computer-aided Design for Manufacturing (DFM) systems play an important role in reducing the time taken for product development by providing manufacturability feedback to the designer while a particular component is being designed. Traditionally, DFM rules are hand-crafted and used to accelerate the engineering product design process by integrating(More)
The 14-3-3 family is a group of intracellular proteins found in all eukaryotic organisms. Humans have seven isoforms that serve as scaffolds to promote interactions of regulatory phospho-proteins involved in many vital cellular processes and previous studies have shown that disturbances in native 14-3-3 levels can contribute significantly to the development(More)