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- Louis Joseph Ignarro, Georgette M. Buga, Keith S. Wood, Russell E Byrns, Gautam Chaudhuri
- Proceedings of the National Academy of Sciences…
- 1987
The objective of this study was to determine whether nitric oxide (NO) is responsible for the vascular smooth muscle relaxation elicited by endothelium-derived relaxing factor (EDRF). EDRF is an… (More)
- Hiroki Kaneko, Sami Dridi, +39 authors Jayakrishna Ambati
- Nature
- 2011
Geographic atrophy (GA), an untreatable advanced form of age-related macular degeneration, results from retinal pigmented epithelium (RPE) cell degeneration. Here we show that the microRNA… (More)
DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88
- V Tarallo, Yoshio Hirano, +26 authors Jayakrishna Ambati
- Cell
- 2012
Alu RNA accumulation due to DICER1 deficiency in the retinal pigmented epithelium (RPE) is implicated in geographic atrophy (GA), an advanced form of age-related macular degeneration that causes… (More)
- Takeshi Hayashi, Jon M Fukuto, Louis Joseph Ignarro, Gautam Chaudhuri
- Proceedings of the National Academy of Sciences…
- 1992
Estradiol is known to exert a protective effect against the development of atherosclerosis, but the mechanism of this hormonal action is unknown. One of the early events in the development of… (More)
- Mark L. Splaingard, Brett Hutchins, L D Sulton, Gautam Chaudhuri
- Archives of physical medicine and rehabilitation
- 1988
This paper reports the results of a blinded study comparing videofluoroscopy with bedside clinical evaluations by speech/language pathologists in the diagnosis of aspiration. One hundred and seven… (More)
- Gautam Chaudhuri, Minu Chaudhuri, Amy Pan, Kwang Poo Chang
- The Journal of biological chemistry
- 1989
Acid proteinase activity is associated with the major surface glycoprotein (gp63) of both extracellular promastigotes and intracellular amastigotes of the parasitic protozoan, Leishmania mexicana.… (More)
- Atila van Nas, Debraj GuhaThakurta, +9 authors Aldons J. Lusis
- Endocrinology
- 2009
We previously used high-density expression arrays to interrogate a genetic cross between strains C3H/HeJ and C57BL/6J and observed thousands of differences in gene expression between sexes. We now… (More)
- Ram Raj Singh, Shehla Pervin, James E. Shryne, Radosław Górski, Gautam Chaudhuri
- Proceedings of the National Academy of Sciences…
- 2000
Sex differences in nitric oxide synthase (NOS) activity in different regions of the rat brain and effects of testosterone and dihydrotestosterone (DHT) treatment in orchidectomized animals were… (More)
- T. K. Mukherjee, Lauren Nathan, Hillary Dinh, Srinivasa T. Reddy, Gautam Chaudhuri
- The Journal of biological chemistry
- 2003
17-beta estradiol (17-beta E(2)) attenuates the expression of vascular cell adhesion molecule 1 (VCAM-1) in vivo at physiological levels (pg/ml), whereas supraphysiological concentrations of 17-beta… (More)
- Shehla Pervin, Rajan Singh, William A. Freije, Gautam Chaudhuri
- Cancer research
- 2003
Apoptosis is regulated by a series of biochemical events that commits a cell to death. We are interested in understanding and have been investigating the mechanisms by which nitric oxide (NO) induces… (More)