Gaurav Kumar Varshney

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The Drosophila melanogaster gene Anaplastic lymphoma kinase (Alk) is homologous to mammalian Alk, a member of the Alk/Ltk family of receptor tyrosine kinases (RTKs). We have previously shown that the Drosophila Alk RTK is crucial for visceral mesoderm development during early embryogenesis. Notably, observed Alk visceral mesoderm defects are highly(More)
In the recent years, the impact of nanometer process technologies has increased capacitive coupling and causing signal noise. Static noise analysis has become the most adopted method for performing signal integrity (SI) checks. This method requires noise characterization data in ASIC cell libraries to avoid spice simulations during chip level analysis.(More)
BACKGROUND In Drosophila muscle cell fusion takes place both during the formation of the somatic mesoderm and the visceral mesoderm, giving rise to the skeletal muscles and the gut musculature respectively. The core process of myoblast fusion is believed to be similar for both organs. The actin cytoskeleton regulator Verprolin acts by binding to WASP, which(More)
C3G is a guanine nucleotide exchange factor (GEF) and modulator of small G-protein activity, which primarily acts on members of the Rap GTPase subfamily. Via promotion of the active GTP bound conformation of target GTPases, C3G has been implicated in the regulation of multiple cellular and developmental events including proliferation, differentiation and(More)
Static noise analysis (SNA) has become the most adopted method for crosstalk noise analysis on multi-million gate designs. Since SNA is vectorless, there exists a need to determine the correct (worst) input vector (the combination of the states of other input pins) for every signal arc in the cell library, to perform noise immunity and noise propagation(More)
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