Gaurav Deshpande

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With the phenomenal growth of wireless networks and applications, it is increasingly important to deliver content efficiently and reliably over wireless links. However, wireless performance is still far from satisfactory due to limited wireless spectrum, inherent lossy wireless medium, and imperfect packet scheduling. While significant research has been(More)
STUDY OBJECTIVE To determine the impact of having an antimicrobial allergy label in the medical record on clinical outcomes in hospitalized patients. DESIGN Retrospective cohort study. SETTING Urban academic teaching hospital. PATIENTS A total of 11,872 adults admitted to nonsurgical patient care wards who received at least one antimicrobial between(More)
Data mining is used in pharmacovigilance as an adjunct to traditional pharmacovigilance practices. There remains ongoing debate as to the impact automated signal detection would have on pharmacovigilance resources. An important component of this debate is the value of each statistical alert or signal of disproportional reporting (SDR) and the resources(More)
PURPOSE First marketed in the USA in 1996, topiramate (TPM) is an antiepileptic drug later approved for migraine prophylaxis, and in 2012 for weight loss in combination with phentermine. Some studies indicate an elevated prevalence of oral cleft (OC) in infants exposed to TPM in utero. We evaluated the association between TPM use in early pregnancy and the(More)
We highlight two fundamental problems that degrade the throughput of wireless mesh networks today. First, severe performance degradation can occur when sources send more traffic than what the network can support. The degradation can be sharp even in a simple setting of a single flow that traverses a network of two links. Second, current routing protocols(More)
BACKGROUND We measured birth prevalence of major congenital malformations (MCMs) after topiramate use during pregnancy to screen for a possible signal of increased risk. METHODS Using four healthcare databases, we identified three cohorts of pregnant women: cohort 1, used topiramate during the first trimester; cohort 2, used topiramate or another(More)
OBJECTIVE To evaluate healthcare resource utilization (HRU) and costs among patients who initiated repository corticotropin injection (RCI; H.P. Acthar Gel) treatment for rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE). METHODS Patients aged ≥18 years with ≥2 diagnoses for either RA or SLE between July 1, 2006 and April 30, 2015 were(More)